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SURF: Announcements of Opportunity

Below are Announcements of Opportunity posted by Caltech faculty and JPL technical staff for the SURF program. Additional AOs for the Amgen Scholars program can be found here.

Specific GROWTH projects being offerred for summer 2019 can be found here.

Each AO indicates whether or not it is open to non-Caltech students. If an AO is NOT open to non-Caltech students, please DO NOT contact the mentor.

Announcements of Opportunity are posted as they are received. Please check back regularly for new AO submissions! Remember: This is just one way that you can go about identifying a suitable project and/or mentor.

Announcements for external summer programs are listed here.

Students pursuing opportunities at JPL must be
U.S. citizens or U.S. permanent residents.

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Project:  Trimodal Peptide for Combined Image-Guided Surgery and Targeted Radiotherapy of Glioblastoma
Disciplines:  Chemistry, Biology
Mentor:  Michael Lewis, Professor, (CCE), LewisMic@missouri.edu, Phone: 573-884-2396
Mentor URL:  http://vhc.missouri.edu/small-animal-hospital/oncology/  (opens in new window)
Background:  NOTE: This project is being offered by a Caltech alum and will be conducted at University of Missouri in Columbia, Missouri.
The overall goal of this project is to develop a radiolabeled, near infrared (NIR) fluorescent, therapeutic, tumor-targeting peptide for multimodal fluorescence imaging, single photon emission computed tomography (SPECT) imaging, and targeted radiotherapy during the course of surgery and of follow-up for glioblastoma multiforme. The hypothesis to be addressed in this project is that the use of this peptide for NIR fluorescence-guided neurosurgery with concomitant targeted radiotherapy, as well as staging by SPECT imaging, will both improve removal of malignant gliomas and provide simultaneous adjuvant radiotherapy.
Description:  The student will radiolabel a tumor-targeting peptide with Lu-177 for targeted radiotherapy and SPECT, purify and characterize it, and help carry out studies of the radiolabeled peptide in cell and animal models of brain cancer.
References:  http://www.sfp.caltech.edu/documents/727-jones_et_al_mi_2018.pdf





Student Requirements:  Introductory courses in chemistry and biology. Chemistry laboratory courses will also be helpful.
Programs:  This AO can be done under the following programs:

  Program    Available To
       SURF    Caltech students only 

Click on a program name for program info and application requirements.


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